So I have posted a lot about the Wuhan Pack (HCQ+Zinc+antibiotic). Social media companies among others are hell bent on telling the public that these medicines and compounds are parts of "conspiracy theories" and "mis-information". Hospitals are firing doctors who speak out and governments are breaching the doctor patient relationship to dictate what the doctors can and cannot prescribe. So lets throw the gauntlet down and show once and for all that HCQ+Zinc is indeed helpful when used early.
Let's go back in time. To 2017 where we find a paper on Zinc and cancer. :
That means, that we can take as much Zinc supplements as we like, and yet that may never get into the cancer cells at the level required to disrupt their normal function.
So what can we do, if we want to push more Zinc into the cancer cells and disrupt their function?
So we see that in the case of cancer patients Zinc is desirable to disrupting cancer. When you are sick (in this case with cancer) you want more Zinc in the cells. How do you do it?
Fortunately, there is a group of chemicals that are called Zinc ionophores (Ref.). Those chemicals have the capability to bind and transport Zinc inside the cancer cell, even if the Zinc transporters are down regulated in cancer cells. Once inside the cancer cell at a level high enough, it has the potential to stop cell functions, regardless of whether we speak about e.g. prostate cancer, etc. with a low level of zinc or e.g. breast cancer with a high level of zinc, prior to Zinc treatment. And the good news is that Zinc ionophores are widely available, used to treat other human problems, while they are also known for their anti cancer action – even when not using Zinc supplementation. Yet, Zinc supplementation is expected to enhance their action.
Say what?
There are things called Zinc Ionophores? Really? We knew this back in 2017 BEFORE the Wuhan virus? I see. And what? They are "widely available" and "used to treat other human problems". You don't say.
Disulfiram is one such Zinc ionophore drug, commonly used as an anti alcohol drug with a long track record of safety in humans (Ref.). As discussed in a previous article (see here) Chloroquine (Ref.) and Clioquinole, both widely available drugs for oral or topical admin., are also Zinc ionophores. Ethambutol, a drug used to treat tuberculosis is also a Zinc ionophore (Ref.1, Ref.2). I will mainly discuss Disulfiram in the following since its effectivenss is already proven, but other Zn ionophores can be considered as well.
Well did I just see Chloroquine?
The Ghost has recommended Quercetin as a substitute for HCQ due to the shameful politicking. Here's a paper on Zinc and Quercetin
Labile zinc, a tiny fraction of total intracellular zinc that is loosely bound to proteins and easily interchangeable, modulates the activity of numerous signaling and metabolic pathways. Dietary plant polyphenols such as the flavonoids quercetin (QCT) and epigallocatechin-gallate act as antioxidants and as signaling molecules. Remarkably, the activities of numerous enzymes that are targeted by polyphenols are dependent on zinc. We have previously shown that these polyphenols chelate zinc cations and hypothesized that these flavonoids might be also acting as zinc ionophores, transporting zinc cations through the plasma membrane.
Laymans terms: Quercetin is a Zinc Ionophore. That paper is from 2014. Are these researchers engaged in "conspiracy theories" and "mis-information"?
Back to the original paper:
For more than 50 years, zinc is known to be an essential trace element, having a regulatory role in the immune system. Deficiency in zinc thus compromises proper immune function, like it is observed in the elderly population. Here mild zinc deficiency is a common condition, documented by a decline of serum or plasma zinc levels with age. This leads to a dysregulation mainly in the adaptive immunity that can result in an increased production of pro-inflammatory cytokines, known as a status called inflamm-aging. T cell activation as well as polarization of T helper (Th) cells into their different subpopulations (Th1, Th2, Th17, regulatory T cells (Treg)) is highly influenced by zinc homeostasis.
So here they are saying that Zinc deficiency compromises immune function. Who's at high risk for COVID? Those with compromised immune function. Who else is at risk for severe COVID? The elderly and the paper explains why. Notice the discussion of T-cells. It is only recently that the role of T-cells has been discussed (The Ghost posted on this already).
So lets review what the literature said back in 2017: Zinc is important for immune function. When sick [with cancer] you want MORE Zinc in your cells. In order to get more Zinc in your cells you need a Zinc ionophore. Chloroquine is a Zinc Ionophore and thus is GOOD to get Zinc into the cell. HydroxyChloroquine is less dangerous than Chloroquine so it is a better choice. You can also use Quercetin as a Zinc ionophore.
All the above statements are true and supported by science known back in 2017 and 2014. What changed in March 2020 to negate this?
Ok. You're saying "but this is for cancer". Fair enough. Lets look at Zinc and actual viri.
Increasing the intracellular Zn(2+) concentration with zinc-ionophores like pyrithione (PT) can efficiently impair the replication of a variety of RNA viruses, including poliovirus and influenza virus. For some viruses this effect has been attributed to interference with viral polyprotein processing.
Say what? "intracellular" means "inside the cell". I'm not trying to be an ass just want to make sure we all understand what we're reading. Now are you ready for the kicker?
In this study we demonstrate that the combination of Zn(2+) and PT at low concentrations (2 µM Zn(2+) and 2 µM PT) inhibits the replication of SARS-coronavirus (SARS-CoV) and equine arteritis virus (EAV) in cell culture.
SARS what?
Oh the date on that paper was November 2014.
2014.
So lets recap again:
Those infected with a SARS-coronavirus would benefit from more Zinc in their cells (just like cancer patients). In order to get the Zinc into the cells you need a Zinc ionophore. Chloroquine, it's less dangerous relation, HydroxyChloroquine or Quercetin are Zinc ionophores. So giving a patient HCQ and extra Zinc allows Zinc into the cells where they "inhibit the replication of SARS-coronovirus".
So this is all known by the "authorities". So they know there is a process that can treat (lessen symptoms in those already sick, possibly prevent symptoms from appearing in those newly infected) The Wuhan virus and they are keeping this information from the public. Social media companies (not run by doctors) are actively censoring DOCTORS who know this information and use it to treat their patients. Hospitals actually firing doctors who speak on using this treatment to save the lives of their patients. All waiting for a Bill Gates paid for vaccine.
